Top Startup Accelerators in Boston in 2025

Boston’s startup ecosystem remains one of the most dynamic in the U.S., powered by top-tier universities, research institutions, and a thriving innovation community. The city’s accelerators offer founders tailored support across sectors—from deep tech and climate innovation to biotech and edtech. Here are the top startup accelerators in Boston in 2025 that are fueling founder success:

Featured Accelerators

1. MassChallenge

Boston’s flagship equity-free accelerator, MassChallenge empowers high-impact startups with mentorship, global networking, and cash awards—without taking equity. Its focus spans a wide range of industries.Startup BostonWikipedia

2. Techstars Boston

Part of the global Techstars network, this program offers intensive mentorship, funding, and industry connections across domains like healthtech, AI, climate, and SaaS—all grounded in Boston’s innovation scene.TechstarsBrandeis University

3. Petri Bio

An accelerator dedicated to biotech and engineering biology startups, Petri Bio provides early-stage funding and deep scientific support in one of the city’s most active sectors.Papermark

4. The Engine

Founded by MIT, The Engine accelerates tough tech ventures tackling scientific and engineering challenges. It offers lab access, corporate partnerships, and long-term venture support.Startup BostonBrandeis University

5. LearnLaunch Accelerator

Focused on edtech innovation, LearnLaunch delivers industry-specific guidance for startups transforming education, with access to investors and a strong local network.Papermark

6. Greentown Labs

North America’s largest climatetech incubator and accelerator, Greentown Labs supports over 200 startups with lab facilities, workshops, and investor introductions in Somerville and beyond.Startup BostonBrandeis University

7. Pagliuca Harvard Life Lab / LabCentral

Harvard’s Pagliuca Life Lab and Cambridge’s LabCentral offer nonprofit lab space, community, and technical infrastructure to biotech founders—equity-free.PapermarkWikipedia

8. Xontogeny

A biotech and biopharma accelerator tailored for life sciences startups, helping companies advance through scientific and commercialization stages.startersss.com

9. Dream Venture Labs

This equity- and fee-free accelerator empowers immigrant and refugee entrepreneurs with mentorship, student volunteer support, and inclusive startup programming.Startup Boston

10. Visible Hands

A Boston-based VC and accelerator, Visible Hands combines capital investment with hands-on support from industry experts to help early-stage companies scale effectively.GrowthMentor

Accelerator Snapshot

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